Title:  Research Development & Sciences – Medical Affairs Operations Manager
Location: Waltham, MA, Hybrid  but will also consider King of Prussia, PA, or potentially 100% remote for the right candidate
Duration: 6 months
Compensation: 70.00- 106.60 per hour
Work Requirements: US Citizen, GC Holders or Authorized to Work in the US
 
Location: Hiring manager strongly prefers a hybrid arrangement in Waltham, MA, but will also consider King of Prussia, PA, or potentially 100% remote for the right candidate
 
Job Description:
 
We are seeking a senior Medical Affairs operator to serve as a force multiplier for the US Medical Affairs leadership team. This individual will act as an operational right hand to the Vice President, translating leadership priorities into disciplined execution across a complex portfolio of cross functional initiatives. This is not a traditional project management role. The successful candidate will operate with strategic context, exercise sound judgment, and proactively drive alignment, prioritization, and follow through across competing priorities. They will ensure that leadership decisions convert into measurable progress, with clear accountability and visibility at all times.
 
Key Responsibilities:
 
Leadership Enablement & Execution
Serve as a trusted operational partner to the VP of US Medical Affairs, supporting execution of strategic priorities across the organization.
Translate leadership vision into executable plans, milestones, and decision points, ensuring nothing falls through the cracks.
Proactively identify risks, dependencies, and trade offs; escalate issues with clarity and recommended actions.
 
Portfolio & Program Orchestration
Maintain real time visibility into active initiatives, timelines, resourcing, and budget utilization across the Medical Affairs portfolio.
Drive prioritization across competing workstreams, balancing urgency, impact, and capacity.
Ensure cross functional alignment across Medical Affairs, Commercial, Clinical, Regulatory, Finance, and other stakeholders as needed.
 
Leadership Team Cadence & Governance
Orchestrate leadership team meetings, including agenda development, pre reads, decision framing, and documented outcomes.
Drive accountable follow through on commitments, decisions, and action items without formal authority.
Establish and maintain effective operating rhythms, governance processes, and communication flows.
 
Operational Rigor & Continuous Improvement
Implement pragmatic tools, trackers, and processes to improve execution discipline without adding unnecessary bureaucracy.
Identify opportunities to streamline workflows, improve visibility, and strengthen operational effectiveness.
Support planning cycles, budget tracking, and resource allocation activities as required.
 
Minimum Requirements:
• 8+ years of experience in Medical Affairs operations, pharmaceutical/biotech program leadership, Chief of Staff–type roles, or equivalent senior operational roles.
• Demonstrated experience supporting VP level or executive leadership in complex, matrixed organizations.
• Strong portfolio or program management capability, with the ability to operate beyond task tracking and timelines.
• Proven ability to influence and hold leaders accountable without positional authority.
• Exceptional organizational judgment, discretion, and executive presence.
• Ability to connect dots across strategy, execution, resourcing, and budget considerations.
• Comfort operating in ambiguity with a strong bias for action.
 
Preferred / Nice to Haves:
• Prior experience in Medical Affairs, R&D, or field medical environments.
• Experience working in hybrid or highly distributed leadership teams.
• Exposure to budget management, resource planning, or operational governance models.
 
What This Role Is — and Is Not
This role is:
• Strategic, leadership adjacent, and execution focused
• Portfolio oriented, not single project delivery
• Accountable for outcomes, not just activity
 
This role is not:
• A junior or mid level project management role
• An administrative or coordinator position
• A role limited to maintaining trackers or scheduling meetings
 
 
Our benefits package includes: (EXCLUDE on perm placements)

• Comprehensive medical benefits
• Competitive pay, 401(k)
• Retirement plan
• …and much more!

 
About INSPYR Solutions:
As a leading information technology partner, we connect top IT talent with our clients to provide innovative business solutions through our IT Staffing, Professional Services, and Infrastructure Solutions divisions. We understand and value the unique needs of highly-skilled information technology professionals in the industry and always strive to stay above the curve. Our company was founded on the following core values: Be the Best, Understand the Urgency, Never Ever Give Up, Have the Courage to Excel, and Make a Contribution. We take pride in our business model and strive to create a positive workplace environment through an exemplary culture.
 
INSPYR Solutions provides Equal Employment Opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, or genetics. In addition to federal law requirements, INSPYR complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities.
 
 

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